Neither a total prevention of biofilm formation nor a complete eradication of a 42 h-old biofilm by any of the tested compounds and the honeys were found. gingivalis biofilms and reduced the numbers of viable bacteria within 42 h-old biofilms. 10% of both types of honey inhibited the formation of P. MICs for hydrogen peroxide were 10 mg/l - 100 mg/l, for methylglyoxal 5 - 20 mg/l, and for propolis 20 mg/l - 200 mg/l. The amount of methylglyoxal was found to be 2 mg/kg in the domestic honey and 982 mg/kg in the Manuka honey. Manuka honey contained 1.87 mg/kg hydrogen peroxide and the domestic honey 3.74 mg/kg. gingivalis, the respective MIC50 of the German beekeeper honey was 5%. RESULTS: 2% of Manuka honey inhibited the growth of 50% of the planktonic P. gingivalis strains in planktonic growth and in a single-species biofilm. These components (up to 100 mg/l), propolis (up to 200 mg/l) as well as the two honeys (up to 10% w/v) were tested against four P.

Contents of methylglyoxal and hydrogen peroxide as the potential antimicrobial compounds were determined. As a screening, MICs of the honeys against 20 P. METHODS: One Manuka and one domestic beekeeper honey have been selected for the study. The in-vitro study was aimed to determine the antimicrobial efficacy against Porphyromonas gingivalis as a major periodontopathogen.

It might be also an alternative to the commonly used antimicrobials in periodontitis treatment.

Conclusion: Anti-microbial properties of honey solution as mouth-rinse did not show any inhibition effect on plaque formation until day 4.īACKGROUND: Honey has been discussed as a therapeutic option in wound healing since ancient time. The fact that the probability value from day 1 (0.766) were gradually decreased to day 4 (0.076). results: There were significant increases of plaque index within each group, but no differences between all three groups in every experimental day. Group I rinse with 5% honey solution, group II with 25%, and group III with aquadest as control. Method: After a thorough prophylaxis, during 4 days period of no oral hygiene all subjects were rinsed with 10 ml mouth-rinse they received 3 times a day after meal. Purpose: To compare the efficacy of 5% and 25% honey solution and aquadest as mouth-rinses to control dental plaque during 4 days period. Honey is a traditional topical treatment for infected wounds and have inhibitory effect to around 60 species of bacteria including aerobes and anaerobes, gram-positives and gram-negatives. Some chemically active substances have been studied as an adjunct to mechanical plaque control. Abstract Background: Periodontal care is an important step of periodontal health management.

Bakteri aerob dan anaerob pdf